HIGH SPRINGS, FL–(Marketwire – December 22, 2009) – CTD Holdings, Inc. (OTCBB: CTDH)
(FRANKFURT: CDJ) announced today that the Company has entered into a Letter
of Intent to form a Joint Venture with J. Jireh Holdings, LLC.

Under the agreement CTD Holdings will contribute cash and other assets to a
joint venture (JV) with J. Jireh which will contribute know how and other
assets. The JV will develop and manufacture proprietary cyclodextrin
complexes and branded products utilizing joint intellectual contributions
and the pulse combustion dryer purchased by the JV. The physical plant is
located and operating in Payson, Arizona.